Squalomix プロジェクト
当研究室では、軟骨魚類について、ゲノム情報をはじめとする分子レベルの包括的な情報を読み取り（オミクス）、生物学的な研究に活用するための取り組み（Squalomixプロジェクト）を、水族館等と連携して進めています。このプロジェクトは、多様な生物のゲノム情報の解読の動きを束ねる世界規模の取り組みであるEBP（Earth Biogenome Project)に加盟しています。初期の活動については、板鰓類研究会会報第57号(2021年12月発行)に掲載された記事で紹介しています。
紹介動画（2021年9月制作）
関連出版論文
原著論文
Shark genomes provide insights into elasmobranch evolution and the origin of vertebrates
Yuichiro Hara, Kazuaki Yamaguchi, Koh Onimaru, Mitsutaka Kadota, Mitsumasa Koyanagi, Sean D. Keeley, Kaori Tatsumi, Kaori Tanaka, Fumio Motone, Yuka Kageyama, Ryo Nozu, Noritaka Adachi, Osamu Nishimura, Reiko Nakagawa, Chiharu Tanegashima, Itsuki Kiyatake, Rui Matsumoto, Kiyomi Murakumo, Kiyonori Nishida, Akihisa Terakita, Shigeru Kuratani, Keiichi Sato, Susumu Hyodo, Shigehiro Kuraku
Nature Ecology and Evolution, 2018. 2: 1761-1771. [ Press release: Japanese / English ]
Cell culture-based shark karyotyping as a resource for chromosome-scale genome analysis.
Yoshinobu Uno, Ryo Nozu, Itsuki Kiyatake, Nobuyuki Higashiguchi, Shuji Sodeyama, Kiyomi Murakumo, Keiichi Sato, Shigehiro Kuraku.
Communications Biology 2020. 3(1): 652.
Whale shark rhodopsin adapted to deep-sea lifestyle by a substitution associated with human disease.
Kazuaki Yamaguchi, Mitsumasa Koyanagi, Keiichi Sato, Akihisa Terakita, Shigehiro Kuraku.
Proc Natl Acad Sci U S A. 2023. 120:e2220728120. [Press release: Japanese]
Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotypic organization
Kazuaki Yamaguchi, Yoshinobu Uno, Mitsutaka Kadota, Osamu Nishimura, Ryo Nozu, Kiyomi Murakumo, Rui Matsumoto, Keiichi Sato Shigehiro Kuraku
Genome Research 2023. In press. doi: 10.1101/gr.276840.122
総説
Visual and non-visual opsin genes of sharks and other non-osteichthyan vertebrates: genomic exploration of underwater photoreception.
Kazuaki Yamaguchi, Mitsumasa Koyanagi,Shigehiro Kuraku.
Journal of Evolutionary Biology 2020. accpeted.
Shark and ray genomics for disentangling their morphological diversity and vertebrate evolution
Shigehiro Kuraku
Developmental Biology 2021. 477: 262-272
その他
Squalomix: shark and ray genome analysis consortium and its data sharing platform [version 1; peer review: awaiting peer review].
Nishimura O, Rozewicki J, Yamaguchi K et al.
F1000Research 2022, 11:1077
The Earth BioGenome Project 2020: Starting the clock.
H. A. Lewin et al.
Proc. Natl. Acad. Sci. U.S.A. 2022. 119: e2115635118.